At the behest of Colonel Stryker, the US Army has developed a device that can ‘cure’ mutants – and rumours abound that Stryker has already started to use the device on mutants labelled as ‘enemies of the state’ – including some of the students at Xavier’s academy. With Magneto’s Brotherhood of Evil Mutants bound to take action, the remaining X Men are dispatched to investigate – and eliminate – the device from Stryker’s secret base deep in the Antarctic wilderness. Ultimately, though, there’s more to the device than meets the eye – and the X-Men will soon find themselves on the brink of full-scale human/mutant war!